Our paper investigates the relationship between breast cancer and Epstein-Barr virus (EBV).

For context, viruses play a causative role for cervical cancer and other cancer types, but the literature is inconclusive on breast cancer.

Our key finding is that protocols used outdated sequences, suggesting that the current understanding of breast cancer may be incomplete.

The paper is done, but would benefit from bioinformatic validation.

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Job

1. Define an established method for determining the number of exact mismatches between PCR primer pairs and the 512 EBV genomes in GenBank.
2. Repeat #1 for nested sequences.
3. Repeat #1 with ambiguous orientations (i.e., the sequence is not stated as 5'->3' or 3'->5').

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Details

Pay: depends on experience.
Authorship: depends on interest.

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Example

This is an example paper in need of mismatch validation: https://pmc.ncbi.nlm.nih.gov/articles/PMC296054.

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Paper

I'm happy to share our paper if you would like to see the findings.

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AI Research

Beyond this job, we need bioinformatic help on other studies related to cancer research and AI biomedicine. Please ask to learn about our research roadmap.